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MolPort-002-705-878

MolPort-002-705-878 is a highly selective FMS-like tyrosine kinase 3 (FLT3) inhibitor with a binding affinity of −11.33 kcal/mol. MolPort-002-705-878 inhibits the proliferation of FLT3-mutated acute myeloid leukemia (AML) cells. MolPort-002-705-878 is promising for research of FLT3-mutated AML[1].

Product Specifications

CAS Number

[304480-98-6]

UNSPSC

12352005

Target

FLT3

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

CC1=CC2=C(NC(/C2=N/NC(C3=C(C=C4C=CC=CC4=C3)O)=O)=O)C=C1Br

Molecular Formula

C20H14BrN3O3

Molecular Weight

424.25

References & Citations

[1]Budha B, et al. Structure-Guided Discovery and Characterization of Novel FLT3 Inhibitors for Acute Myeloid Leukemia Treatment[J]. bioRxiv, 2025: 2025.06. 26.661886.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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