MolPort-002-705-878
MolPort-002-705-878 is a highly selective FMS-like tyrosine kinase 3 (FLT3) inhibitor with a binding affinity of −11.33 kcal/mol. MolPort-002-705-878 inhibits the proliferation of FLT3-mutated acute myeloid leukemia (AML) cells. MolPort-002-705-878 is promising for research of FLT3-mutated AML[1].
Product Specifications
CAS Number
[304480-98-6]
UNSPSC
12352005
Target
FLT3
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
CC1=CC2=C(NC(/C2=N/NC(C3=C(C=C4C=CC=CC4=C3)O)=O)=O)C=C1Br
Molecular Formula
C20H14BrN3O3
Molecular Weight
424.25
References & Citations
[1]Budha B, et al. Structure-Guided Discovery and Characterization of Novel FLT3 Inhibitors for Acute Myeloid Leukemia Treatment[J]. bioRxiv, 2025: 2025.06. 26.661886.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items