EGFR-IN-47-C6-COOMe
EGFR-IN-47-C6-COOMe is a synthesized target protein ligand-linker conjugate that can be used for synthesis of PROTACs, such as PROTAC EGFR degrader 14 (HY-175252) . PROTAC EGFR degrader 14 is a EGFR PROTAC degrader with anti-tumor activity[1].
Product Specifications
UNSPSC
12352005
Target
Target Protein Ligand-Linker Conjugates
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(CCCCCCN1CCN(C2=CC=C(NC3=NC=C4C(N(C(CNC5=CC=CC=C5)=C4)C6CCCC6)=N3)C=C2)CC1)OC
Molecular Formula
C36H47N7O2
Molecular Weight
609.80
References & Citations
[1]Wang X, et al. Discovery of a Novel EGFR PROTAC Degrader against C797S Resistance Mutation with Potent Antitumor Efficacy in NSCLC Treatment. J Med Chem. 2025 Jul 24;68 (14) :14569-14593.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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