Antibiofilm agent-17
Antibiofilm agent-17 is a dual-action biofilm inhibitor against Pseudomonas aeruginosa (IC50 = 0.33 μM) . Antibiofilm agent-17 inhibits biofilm growth by reducing quorum sensing-mediated virulence production and iron ion acquisition. Antibiofilm agent-17 exhibits synergistic antimicrobial effects in a mouse wound infection model. Antibiofilm agent-17 can be used in research on combating Pseudomonas aeruginosa infections[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
CC(N(C(CNC(CCCC(NC1=CC=CC(OC)=C1)=O)=O)=C2O)C)=CC2=O
Molecular Formula
C20H25N3O5
Molecular Weight
387.43
References & Citations
[1]Long HZ, et al. Discovery of Dual-Acting Biofilm Inhibitors against Pseudomonas aeruginosa by the Coupling of 3-Hydroxypyridin-4 (1H) -ones with N-Phenylamide QS Inhibitors. J Med Chem. 2025 Jul 24;68 (14) :14756-14781.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
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