TKL-IN-2

TKL-IN-2 (Compound 7m) is a TKL inhibitor with an IC50 of 0.11 mg/L against SvTKL. TKL-IN-2 exhibits excellent herbicidal activity against Digitaria sanguinalis and Amaranthus retroflexus, and is safe for maize, wheat, soybean, and cotton. TKL-IN-2 can be used in research on weed control in crop fields[1].

Product Specifications

CAS Number

[3082627-31-1]

UNSPSC

12352005

Target

Herbicide; Transketolase

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Smiles

O=C(NC1=CC=C(C=C1)C(F)(F)F)CC2=CN(C3=C2C=CC=C3)CC4=CC=C(N=C4)Cl

Molecular Formula

C23H17ClF3N3O

Molecular Weight

443.85

References & Citations

[1]Wang YE, et al. Discovery of Indole-3-acetamide Derivatives as Potent Transketolase-Inhibiting-Based Herbicidal Leads. J Agric Food Chem. 2025 Jul 23;73 (29) :18119-18130.