PSMA-DIM
PSMA-DIM is a dimeric PSMA ligand with a Kd of 37.09 nM for LNCaP cells. PSMA-DIM can be radiolabeled with [68Ga]Ga to form [68Ga]Ga-PSMA-DIM. [68Ga]Ga-PSMA-DIM can effectively distinguish between cells and animal models with different expression levels of PSMA. [68Ga]Ga-PSMA-DIM exhibits high LNCaP cells uptake and tumor uptake peak values. PSMA-DIM can be used for the study of prostate cancer (PCa) [1].
Product Specifications
UNSPSC
12352211
Target
PSMA
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Smiles
IC1=CC=C(C=C1)CCCC(NCCCCC(C(NC(CCC(NCCOCCOCCOCCOCC(NC2CCN(C(N[C@H](C(NCCCC[C@@H](C(O)=O)NC(N[C@@H](CCC(O)=O)C(O)=O)=O)=O)CC3=CC=C4C=CC=CC4=C3)=O)CC2)=O)=O)C(NCCOCCOCCOCCOCC(NC5CCN(C(N[C@H](C(NCCCC[C@@H](C(O)=O)NC(N[C@@H](CCC(O)=O)C(O)=O)=O)=O)CC6=CC=C7C=CC=CC7=C6)=O)CC5)=O)=O)=O)NC(CN8CCN(CCN(CCN(CC8)CC(O)=O)CC(O)=O)CC(O)=O)=O)=O
Molecular Formula
C119H174IN21O39
Molecular Weight
2649.68
References & Citations
[1]Quan Xie, et al. Preclinical Evaluation Study of 68Ga-Labeled PSMA-Targeted Dimer Probe. pubs.acs.org. 2025 Jun 10.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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