CAIX-IN-4
CAIX-IN-4 (Compound 8b) is a selective carbonic anhydrase IX (CAIX) inhibitor with an IC50 value of 0.32 μM. CAIX-IN-4 is promising for research of cancers such as renal cell carcinoma[1].
Product Specifications
UNSPSC
12352005
Target
Carbonic Anhydrase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
O=C1C(C2=CSC(NC34C[C@H]5C[C@](C4)([H])C[C@@](C5)([H])C3)=N2)=CC6=C(O1)C=CC(Br)=C6
Molecular Formula
C22H21BrN2O2S
Molecular Weight
457.38
References & Citations
[1]Ahmed A, et al. Synthesis and evaluation of thiazolyl coumarin drug conjugates as carbonic anhydrase isozyme inhibitors by using integrated invitro and insilico approaches. Sci Rep. 2025 Jul 1;15 (1) :22032.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CA IX
Curated Selection
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