CA-II/Dkk1-IN-1
CA-II/Dkk1-IN-1 (Compound 5d) is a dual-functional inhibitor of CA-II and Dkk1 with a IC50 of 6.90 nM for CA-II. CA-II/Dkk1-IN-1 has significantly antioxidant activity and superior DNA binding capacity. CA-II/Dkk1-IN-1 can be used for cancers research, such as esophageal, renal, and lung cancer[1].
Product Specifications
UNSPSC
12352005
Target
Carbonic Anhydrase
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=S(C1=CC=C(NC(S2)=NC(C2=C(C3=CC4=C(C=C3)N(CC)C5=C4C=CC=C5)N6)=NC6=S)C=C1)(N)=O
Molecular Formula
C25H20N6O2S3
Molecular Weight
532.66
References & Citations
[1]Bilal MS, et al. Synthesis, in vitro evaluation and computational modelling of benzene sulfonamide derivatives as Dickkopf 1 inhibitors for anticancer drug development. Sci Rep. 2025 Jul 1;15 (1) :21049.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CA II
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
PKSV030352 100 µg
Recombinant SARS-CoV-2 Spike RBD (N501Y) (His Tag)
Sign In for Pricing
View Details 