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Maleimide-Ph (3,5-F) -PEG4-Val-Ala

Maleimide-Ph (3,5-F) -PEG4-Val-Ala is a cleavable PEG-based ADC linker that can be used in the synthesis of antibody-drug conjugates (ADCs) [1].

Product Specifications

UNSPSC

12352005

Target

ADC Linker

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

FC(C=C1N2C(C=CC2=O)=O)=C(C(F)=C1)OCCOCCOCCOCC(N[C@@H](C(C)C)C(N[C@H](C(O)=O)C)=O)=O

Molecular Formula

C26H33F2N3O10

Molecular Weight

585.55

References & Citations

[1]Wang R, et al. Overcoming multidrug resistance in gastrointestinal cancers with a CDH17-targeted ADC conjugated to a DNA topoisomerase inhibitor. Cell Rep Med. 2025 Jul 15;6 (7) :102213.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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