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Nrf2 activator-20

Nrf2 activator-20 is a potent Nrf2 activator with anti-inflammatory and antioxidant activities. Nrf2 activator-20 activates the anti-inflammatory pathway by interfering with the Keap1-Nrf2 interaction and is beneficial in vivo. Nrf2 activator-20 can be used for the study of acute respiratory distress syndrome (ARDS) and ischemia-reperfusion injury[1].

Product Specifications

CAS Number

[89883-16-9]

UNSPSC

12352100

Target

Keap1-Nrf2

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Smiles

O=C1C(Br)=C(Br)C(O)(C)C=C1Br

Molecular Formula

C7H5Br3O2

Molecular Weight

360.83

References & Citations

[1]Latreille E, et al. Phenotypic screening in influenza-infected zebrafish identifies Nrf2-mediated compound protective against ischemia-reperfusion injury. iScience. 2025 Jul 4;28 (8) :113065.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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