CHI3L1-IN-3
CHI3L1-IN-3 is a CHI3L1 inhibitor. CHI3L1-IN-3 binds to CHI3L1 with Kds of 13.76 μM and 13.5 μM in MST and SPR assays, respectively. CHI3L1-IN-3 demonstrates extended plasma half-lives and microsomal stability, along with reduced intrinsic clearance. CHI3L1-IN-3 induces dose-dependent cytotoxicity, reduces spheroid mass and inhibits migration in a 3D multicellular glioblastoma (GBM) spheroid model. CHI3L1-IN-3 can be used for the study of GBM[1].
Product Specifications
UNSPSC
12352005
Target
Glycosidase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Purity
98.95
Smiles
COC(C(OC)=C1)=CC(C2=O)=C1N=C(SCC(NC3=CC=C(CC)C=C3)=O)N2CCC4=CC=C(OC)C(OC)=C4
Molecular Formula
C30H33N3O6S
Molecular Weight
563.66
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature, keep dry and cool
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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