CIDD-8633
CIDD-8633 is a potent DDR2 inhibitor with an IC50 of 6.105 μM. CIDD-8633 inhibits cell migration and halts the cell cycle and induces apoptosis, significantly suppressing pancreatic ductal adenocarcinoma (PDAC) tumor growth. CIDD-8633 can be used for the study of pancreatic cancer such as PDAC[1].
Product Specifications
CAS Number
1428356-95-9
UNSPSC
12352005
Target
Apoptosis; Caspase; Discoidin Domain Receptor; Interleukin Related; PERK
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Immunology/Inflammation; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
O=C(NC1=CC=C(NC2=NC(NCC)=NC(C)=C2)C=C1)COC(C=C3)=NN=C3N4C=CC=N4
Molecular Formula
C22H23N9O2
Molecular Weight
445.48
References & Citations
[1]Do CT, et al. Targeting DDR2 for Treating Pancreatic Cancer. Mol Cancer Ther. 2025 Jun 26.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Caspase 3; DDR2; IL-6
Frequently Asked Questions
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