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Cs-2d

Cs-2d is a selective ceramide synthases Cer1 inhibitor. Cs-2d has potent inhibitory activity toward C. neoformans Cer1, while maintaining a low off-target effect on human hCerS1. Cs-2d has potent antifungal activity with the significant growth inhibition. Cs-2d can be used for invasive fungal infections research[1].

Product Specifications

CAS Number

2928129-57-9

UNSPSC

12352005

Target

Acyltransferase; Fungal

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Infection

Smiles

NCCCCCN1C(C2=C(C)C=C(OCO3)C3=C2)=C(C4=CC=CC=C4)N=C1.Cl.Cl

Molecular Formula

C22H27Cl2N3O2

Molecular Weight

436.37

References & Citations

[1]Dasilva D, et al. Targeting ceramide synthases for the development of new antifungals. Structure. 2025 Jun 12:S0969-2126 (25) 00213-8.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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