Cs-2d
Cs-2d is a selective ceramide synthases Cer1 inhibitor. Cs-2d has potent inhibitory activity toward C. neoformans Cer1, while maintaining a low off-target effect on human hCerS1. Cs-2d has potent antifungal activity with the significant growth inhibition. Cs-2d can be used for invasive fungal infections research[1].
Product Specifications
CAS Number
[2928129-57-9]
UNSPSC
12352005
Target
Acyltransferase; Fungal
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
NCCCCCN1C(C2=C(C)C=C(OCO3)C3=C2)=C(C4=CC=CC=C4)N=C1.Cl.Cl
Molecular Formula
C22H27Cl2N3O2
Molecular Weight
436.37
References & Citations
[1]Dasilva D, et al. Targeting ceramide synthases for the development of new antifungals. Structure. 2025 Jun 12:S0969-2126 (25) 00213-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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