P2X7 receptor antagonist-6
P2X7 receptor antagonist-6 (Compound 2g) is a negative allosteric P2X7 receptor antagonist with an IC50 of 1.31 μM for hP2X7. P2X7 receptor antagonist-6 can be used for cancer, neurodegenerative, inflammatory, and infectious diseases research[1].
Product Specifications
CAS Number
1114621-31-6
UNSPSC
12352005
Target
P2X Receptor
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cancer; Infection; Inflammation/Immunology; Neurological Disease
Smiles
O=C(NC(CC1=CC=C(C=C1)F)CC2=CC=C(C=C2)F)NC3=CC4=C(OCO4)C=C3
Molecular Formula
C23H20F2N2O3
Molecular Weight
410.41
References & Citations
[1]Zuanon M, et al. Identification of New Human P2X7 Antagonists Using Ligand- and Structure-Based Virtual Screening. J Chem Inf Model. 2025 Jul 14;65 (13) :7143-7155.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P2X7 Receptor
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