P2X7 receptor antagonist-6
P2X7 receptor antagonist-6 (Compound 2g) is a negative allosteric P2X7 receptor antagonist with an IC50 of 1.31 μM for hP2X7. P2X7 receptor antagonist-6 can be used for cancer, neurodegenerative, inflammatory, and infectious diseases research[1].
Product Specifications
CAS Number
[1114621-31-6]
UNSPSC
12352005
Target
P2X Receptor
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cancer; Infection; Inflammation/Immunology; Neurological Disease
Smiles
O=C(NC(CC1=CC=C(C=C1)F)CC2=CC=C(C=C2)F)NC3=CC4=C(OCO4)C=C3
Molecular Formula
C23H20F2N2O3
Molecular Weight
410.41
References & Citations
[1]Zuanon M, et al. Identification of New Human P2X7 Antagonists Using Ligand- and Structure-Based Virtual Screening. J Chem Inf Model. 2025 Jul 14;65 (13) :7143-7155.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P2X7 Receptor
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
