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GABA receptor antagonist 2

GABA receptor antagonist 2 (Compound IId) is a GABA receptor antagonist with a LC50 of 0.0735 μg/mL for Plutella xylostella (P. xylostella) . GABA receptor antagonist 2 has significant insecticidal activities against P. xylostella and its resistant strain, and Spodoptera frugiperda, and Chilo suppressalis. GABA receptor antagonist 2 binds the GABA receptor at the site of Drosophila RdlG335. GABA receptor antagonist 2 can be used to manage resistant pest populations[1].

Product Specifications

CAS Number

2922115-20-4

UNSPSC

12352005

Target

GABA Receptor

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Smiles

FC(C(F)(F)F)(C(F)(F)F)C1=CC(Br)=C(C(C(F)(F)F)=C1)NC(C2=C(C(N(C(C3=CC=C(C=C3)F)=O)CCOC)=CC=C2)F)=O

Molecular Formula

C27H17BrF12N2O3

Molecular Weight

725.32

References & Citations

[1]Zhou S, et al. Design, Synthesis, and Insecticidal Activities of Novel N-Alkoxyalkyl Meta-Diamides as Potential GABAR Antagonists. J Agric Food Chem. 2025 Jul 16;73 (28) :17446-17457.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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