LSD1-IN-44
LSD1-IN-44 (Compound 19) is a LSD1 inhibitor with an IC50 of 0.02 μM for LSD1-CoREST enzymatic complex. LSD1-IN-44 has significant antischistosomal activity against transformed schistosomula (NTS) and Schistosoma mansoni adult worms while showing a delayed onset of action towards juvenile forms. LSD1-IN-44 has no significant toxicity to human cells. LSD1-IN-44 can be used for schistosomiasis research[1].
Product Specifications
UNSPSC
12352300
Target
Histone Demethylase
Related Pathways
Epigenetics
Field of Research
Infection
Smiles
O=C(NC1=CC=C(C2C(N)C2)C=C1)C3=CC=C(C#CC4CC4)C=C3.Cl
Molecular Formula
C21H21ClN2O
Molecular Weight
352.86
References & Citations
[1]Fabbrizi E, et al. Tranylcypromine-Based LSD1 Inhibitors as Useful Agents to Reduce Viability of Schistosoma mansoni. ACS Infect Dis. 2025 Jul 2.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
KDM1/LSD1
Frequently Asked Questions
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