Antituberculosis agent-15
Antituberculosis agent-15 (Compound 18c) is a selective antimycobacterial agent with MICs of 0.45 and 0.28 μM for M. tuberculosis H37Rv (ATCC 27294) and its wild-type H37Rv-LP (ATCC 25618), respectively. Antituberculosis agent-15 has potent intracellular inhibitory activities in macrophage infection models with IC50s of 0.16 μM. Antituberculosis agent-15 can be used for tuberculosis research[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
CC1=NC(NCCCC2=CC=CC=C2)=C3C=C(Br)C=CC3=N1
Molecular Formula
C18H18BrN3
Molecular Weight
356.26
References & Citations
[1]Gonçalves GA, et al. Scaffold Hopping Strategy toward New 4‑Aminoquinazolines Active Against Extracellular and Intracellular. ACS Med Chem Lett. 2025 Jun 30;16 (7) :1410-1419.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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