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BMS-025

BMS-025 is a orthosteric STING agonist. BMS-025 can induces chemical shift of STING M271 residue, further activating STING IFN signaling. BMS-025 can be used for monogenic autoinflammatory disease like SAVI disease research[1].

Product Specifications

UNSPSC

12352005

Target

STING

Related Pathways

Immunology/Inflammation

Field of Research

Inflammation/Immunology

Smiles

NC1=C2N=CN(C2=NC=N1)[C@@H]3C[C@@H]4OP(S)(OC[C@H]5O[C@H]([C@@H]([C@@H]5O)OP(S)(OC[C@H]43)=O)N6C=NC7=C6N=C8NC=CN8C7=O)=O

Molecular Formula

C22H24N10O9P2S2

Molecular Weight

698.57

References & Citations

[1]Xie T, et al. Orthosteric STING inhibition elucidates molecular correction of SAVI STING. Nat Commun. 2025 Jul 1;16 (1) :5695.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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