BMS-025
BMS-025 is a orthosteric STING agonist. BMS-025 can induces chemical shift of STING M271 residue, further activating STING IFN signaling. BMS-025 can be used for monogenic autoinflammatory disease like SAVI disease research[1].
Product Specifications
UNSPSC
12352005
Target
STING
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
NC1=C2N=CN(C2=NC=N1)[C@@H]3C[C@@H]4OP(S)(OC[C@H]5O[C@H]([C@@H]([C@@H]5O)OP(S)(OC[C@H]43)=O)N6C=NC7=C6N=C8NC=CN8C7=O)=O
Molecular Formula
C22H24N10O9P2S2
Molecular Weight
698.57
References & Citations
[1]Xie T, et al. Orthosteric STING inhibition elucidates molecular correction of SAVI STING. Nat Commun. 2025 Jul 1;16 (1) :5695.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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