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2-Fluorodeoxyarbutin

2-Fluorodeoxyarbutin, a derivative of Deoxyarbutin (HY-B1461), is a tyrosine hydroxylase and dopa oxidase inhibitor. 2-Fluorodeoxyarbutin inhibits melanin synthesis in intact melanocytes. 2-Fluorodeoxyarbutin can be used for the strudy of skin lightening or for ameliorating hyperpigmented lesions[1].

Product Specifications

CAS Number

[170795-16-1]

UNSPSC

12352005

Target

Tyrosine Hydroxylase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Smiles

OC1=CC=C(OC2CCCCO2)C=C1F

Molecular Formula

C11H13FO3

Molecular Weight

212.22

References & Citations

[1]Chawla S, et al. DeoxyArbutin and its derivatives inhibit tyrosinase activity and melanin synthesis without inducing reactive oxygen species or apoptosis. J Drugs Dermatol. 2012 Oct;11 (10) :e28-34.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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