Guanine-2'-deoxy-β-L-ribofuranosyl-5'-O-triphosphate (sodium)

Guanine-2'-deoxy-β-L-ribofuranosyl-5'-O-triphosphate (sodium) is an isomer of dGTP and an inhibitor of telomerase with a Ki of 15 μM for human enzyme[1].

Product Specifications

Product Name Alternative

β-L-dGTP (sodium) ; L-2'-Deoxyguanosine 5'-triphosphate (sodium) ; 2’-Deoxy-L-GTP (sodium)

UNSPSC

12352005

Target

Telomerase

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Smiles

NC1=NC(C2=C(N1)N(C=N2)[C@H](C[C@H]3O)O[C@H]3COP(OP(OP(O[Na])(O[Na])=O)(O[Na])=O)(O)=O)=O.[NaH]

Molecular Formula

C10H14N5Na4O13P3

Molecular Weight

597.12

References & Citations

[1]Yamaguchi, T., et al., (2000) . Recognition of 2'-deoxy-l-ribonucleoside 5'-triphosphates by human telomerase. Biochemical and biophysical research communications, 279 (2), 475–481.