D-myo-Inositol-1,2,4,5,6-pentaphosphate (sodium salt)

D-myo-Inositol-1,2,4,5,6-pentaphosphate (Ins (1,2,4,5,6) P5) sodium salt is one of several different inositol oligophosphate isomers involved in signal transduction. In human Jurkat T lymphocytes, Ins (1,2,4,5,6) P5 (sodium salt) is phosphorylated to InsP6 by 1/3 kinase. D-myo-Inositol-1,2,4,5,6-pentaphosphate sodium salt is involved in calcium signaling[1].

Product Specifications

Product Name Alternative

Ins (1,2,4,5,6) P5 (sodium salt) ; 1,2,4,5,6-IP5 (sodium salt)

UNSPSC

12352211

Target

Calcium Channel

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Others

Smiles

O[C@@H]1[C@H](OP(O)(O[Na])=O)[C@H](OP(O)(O[Na])=O)[C@@H](OP(O)(O[Na])=O)[C@H](OP(O)(O[Na])=O)[C@H]1OP(O)(O[Na])=O

Molecular Formula

C6H12Na5O21P5

Molecular Weight

689.96

References & Citations

[1]Guse AH, et al. T-cell receptor-mediated metabolism of inositol polyphosphates in Jurkat T-lymphocytes. Identification of a D-myo-inositol 1,2,3,4,6-pentakisphosphate-2-phosphomonoesterase activity, a D-myo-inositol 1,3,4,5,6-pentakisphosphate-1/3-phosphatase activity and a D/L-myo-inositol 1,2,4,5,6-pentakisphosphate-1/3-kinase activity. J Biol Chem. 1991 Dec 25;266 (36) :24498-502.