8-DY547-cGMP
8-DY547-cGMP is a fluorescent cGMP analogue composed of a dye DY547 to position 8 of cGMP. 8-DY547-cGMP is a Cyclic nucleotide-gated A2 (CNGA2) ligand. 8-DY547-cGMP can activated CNGA2 channel. 8-DY547-cGMP can be used for simultaneously detection CNG channel activation and ligand binding[1].
Product Specifications
UNSPSC
12352005
Target
Drug Derivative; Fluorescent Dye
Related Pathways
Others
Field of Research
Others
Smiles
CC[N+]1=C(/C=C/C=C2C(C)(C3C=C(C=CC3N/2CC)S(=O)(O[Na])=O)CCCC(NCCSC4NC5C(NC(N)=NC5N4C6OC7COP(OC7C6O)(O[Na])=O)=O)=O)C(C)(C)C8=C1C=C(C=C8)S(=O)([O-])=O
Molecular Formula
C42H55N8Na2O14PS3
Molecular Weight
1069.08
References & Citations
[1]Biskup C, et al. Relating ligand binding to activation gating in CNGA2 channels. Nature. 2007 Mar 22;446 (7134) :440-3.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
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