8-iso Prostaglandin F2α ethanolamide

8-isoprostaglandin F2α ethanolamide (iPF2α-III ethanolamide; 8-Isoprostane ethanolamide; 8-iso PGF2α ethanolamide) is an isoprostanol ethanolamide derivative derived from anandamide (AEA) via non-enzymatic free radical oxidation. 8-isoprostaglandin F2α ethanolamide is commonly used as a marker of oxidative stress, distinguishing non-enzymatic degradation products from "prostamides" generated by enzymatic pathways such as COX-2[1].

Product Specifications

Product Name Alternative

IPF2α-III ethanolamide; 8-Isoprostane ethanolamide; 8-iso PGF2α ethanolamide

UNSPSC

12352211

Target

Drug Derivative

Related Pathways

Others

Field of Research

Others

Smiles

O[C@@H]1[C@H]([C@H]([C@@H](C1)O)/C=C/[C@H](CCCCC)O)C/C=C\CCCC(NCCO)=O

Molecular Formula

C22H39NO5

Molecular Weight

397.55

References & Citations

[1]Weber A, et al. Formation of prostamides from anandamide in FAAH knockout mice analyzed by HPLC with tandem mass spectrometry. J Lipid Res. 2004 Apr;45 (4) :757-63.