Rosuvastatin (Sodium) (Standard)
Rosuvastatin (Sodium) (Standard) is the analytical standard of Rosuvastatin (Sodium) . This product is intended for research and analytical applications. Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC50 of 195 nM[2]. Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels[1][2][3].
Product Specifications
CAS Number
[147098-18-8]
UNSPSC
12352100
Target
Autophagy; Bacterial; HMG-CoA Reductase (HMGCR) ; Potassium Channel; Reference Standards
Related Pathways
Anti-infection; Autophagy; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease; Cardiovascular Disease; Cancer
Smiles
O=C(O[Na])C[C@H](O)C[C@H](O)/C=C/C1=C(C(C)C)N=C(N(C)S(=O)(C)=O)N=C1C2=CC=C(F)C=C2
Molecular Formula
C22H27FN3NaO6S
Molecular Weight
503.52
References & Citations
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-17504BR/
Scientific Category
Reference Standards
Available Sizes
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