Enpp-1-IN-26
Enpp-1-IN-26 (Compound 4e) is an ENPP1 inhibitor with an IC50 of 0.188 μM. Enpp-1-IN-26 enhances IFN-β expression in vivo by preventing ENPP1 from hydrolyzing cGAMP. Enpp-1-IN-26 can be used in the research of metastatic breast cancer[1].
Product Specifications
CAS Number
[2848714-91-8]
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
FC1=CC2=C(C(NC(CSC3=NC4=NC(OC)=CC=C4N3)=N2)=O)C=C1
Molecular Formula
C16H12FN5O2S
Molecular Weight
357.36
References & Citations
[1]Wang X, et al. Development of Novel Ecto-Nucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) Inhibitors for Tumor Immunotherapy. Int J Mol Sci. 2022 Jun 26;23 (13) :7104.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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