Oomycete-IN-1
Oomycete-IN-1 (Compound X4) is a selective inhibitor targeting the PH domain of PcORP1 in Phytophthora species. Oomycete-IN-1 shows EC50 values ranging from 1 to 4 μg/mL against six oomycetes. Oomycete-IN-1 disrupts lipid transport and metabolism, leading to mycelium hyperplasia and cell membrane ruffling in P. capsici. Oomycete-IN-1 can be used in the research of preventing and controlling oomycete diseases (such as P. capsici infection) [1].
Product Specifications
UNSPSC
12352005
Target
Fungal
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
CN1N=C(C(F)F)C(C(N/N=C/C=C/C2=CC=CC=C2)=O)=C1
Molecular Formula
C15H14F2N4O
Molecular Weight
304.29
References & Citations
[1]Lu X, et al. Discovery of novel inhibitors targeting the PH domain of PcORP1: Virtual screening, structural optimization, biological evaluation. Eur J Med Chem. 2025 Oct 15;296:117900.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-175038/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
CAS Number
[2945180-71-0]
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