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Oomycete-IN-1

Oomycete-IN-1 (Compound X4) is a selective inhibitor targeting the PH domain of PcORP1 in Phytophthora species. Oomycete-IN-1 shows EC50 values ranging from 1 to 4 μg/mL against six oomycetes. Oomycete-IN-1 disrupts lipid transport and metabolism, leading to mycelium hyperplasia and cell membrane ruffling in P. capsici. Oomycete-IN-1 can be used in the research of preventing and controlling oomycete diseases (such as P. capsici infection) [1].

Product Specifications

CAS Number

[2945180-71-0]

UNSPSC

12352005

Target

Fungal

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

CN1N=C(C(F)F)C(C(N/N=C/C=C/C2=CC=CC=C2)=O)=C1

Molecular Formula

C15H14F2N4O

Molecular Weight

304.29

References & Citations

[1]Lu X, et al. Discovery of novel inhibitors targeting the PH domain of PcORP1: Virtual screening, structural optimization, biological evaluation. Eur J Med Chem. 2025 Oct 15;296:117900.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-175038/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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