ATF3-IN-1
ATF3-IN-1 is a ferroptosis and ATF3 inhibitor. ATF3-IN-1 inhibits oxidative stress and ferroptosis through the ATF3/SLC7A11/GPX4 pathway, exerting anti-ischemic stroke effects. ATF3-IN-1 can attenuate ischemia/reperfusion (I/R) injury and improve neuronal survival. ATF3-IN-1 has neuroprotective effects and can be used to study ischemic stroke[1].
Product Specifications
CAS Number
2952703-90-9
UNSPSC
12352005
Target
Epigenetic Reader Domain; Ferroptosis; Glutathione Peroxidase; Reactive Oxygen Species (ROS)
Related Pathways
Apoptosis; Epigenetics; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease; Cardiovascular Disease
Purity
96.30
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N1CCOCC1)OCCCCCCCCCCC2=C(C)C(C(OC)=C(OC)C2=O)=O
Molecular Formula
C24H37NO7
Molecular Weight
451.55
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
GPX4
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis) (ELN/1981), CF488A conjugate, 0.1mg/mL
Human Bactericidal permeability-increasing protein ELISA Kit
Human Bactericidal permeability-increasing protein ELISA Kit
Human Bactericidal permeability-increasing protein ELISA Kit