MC12
MC12 is a thiazole-based derivative and a SARS-CoV-2 main protease inhibitor (IC50: 77.7 nM) . MC12 exhibits inhibitory effects on both SARS-CoV and SARS-CoV-2 main proteases, with low cytotoxicity and good stability. MC12 can be used in the research of anti-COVID-19 drugs[1].
Product Specifications
UNSPSC
12352005
Target
SARS-CoV; Virus Protease
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
ClC1=CN=CC(OC(C2=CSC(N(C)C3=CC=CC=C3)=N2)=O)=C1
Molecular Formula
C16H12ClN3O2S
Molecular Weight
345.80
References & Citations
[1]Yin W, et al. Structure-activity relationship studies of thiazole-based derivatives leading to the identification of novel and potent SARS-CoV-2 main protease inhibitors. Eur J Med Chem. 2025 Jul 7;297:117952.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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