OncoACP3 (TFA)
OncoACP3 TFA (Compound s43) is a high affinity ligand for prostatic acid phosphatase (ACP3) . OncoACP3 TFA, radiolabelled with Lu-177, selectively accumulates in enzyme-expressing tumors and shows a potent anti-tumor activity with excellent tumor-selective payload deposition in HT1080.hACP3 and PC3.hACP3 tumor-bearing mice model. OncoACP3 TFA can be used for prostate cancer research[1].
Product Specifications
UNSPSC
12352211
Target
Phosphatase
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.87
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC(CN1CCN(CC(NCCCCCCNC([C@H]2N(C(CN(CC3=CC=CC=C3)CC4=CC=CC=C4)=O)C[C@@H](N5N=NC(COC6=CC=C(C(NCC7=CC=CC=C7)P(O)(O)=O)C=C6)=C5)C2)=O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1)=O.OC(C(F)(F)F)=O
Molecular Formula
C62H82F3N12O15P
Molecular Weight
1323.35
References & Citations
[1]Georgiev T, et al. Discovery of high-affinity ligands for prostatic acid phosphatase via DNA-encoded library screening enables targeted cancer therapy. Nat Biomed Eng. 2025 Jun 26.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LY402217 100 µg
Tin2 (TINF2) (NM_012461) Human Over-expression Lysate
Sign In for Pricing
View Details