SARS-CoV-2 Mpro-IN-46
SARS-CoV-2 Mpro-IN-46 (Compound 12) is a SARS-CoV-2 main protease inhibitor with an IC50 of ∼25 μM. SARS-CoV-2 Mpro-IN-46 has potent antiviral activity with low cytotoxicity against SARS-CoV-2 (IC50: 7.4 μM) . SARS-CoV-2 Mpro-IN-46 can be used for coronaviruses COVID-19 research[1].
Product Specifications
CAS Number
[1800004-01-6]
UNSPSC
12352005
Target
SARS-CoV
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
ClC1=CC2=C(C(NC3=CC=C(C(C4=CC=CC=C4)=C3)CN5CCCC5)=CC=N2)C=C1
Molecular Formula
C26H24ClN3
Molecular Weight
413.94
References & Citations
[1]Dávila B, et al. Unveiling novel pharmacophores and hit compounds for the development of anti-virals to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) . Bioorg Chem. 2025 Jul 4;163:108724.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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