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SARS-CoV-2 Mpro-IN-46

SARS-CoV-2 Mpro-IN-46 (Compound 12) is a SARS-CoV-2 main protease inhibitor with an IC50 of ∼25 μM. SARS-CoV-2 Mpro-IN-46 has potent antiviral activity with low cytotoxicity against SARS-CoV-2 (IC50: 7.4 μM) . SARS-CoV-2 Mpro-IN-46 can be used for coronaviruses COVID-19 research[1].

Product Specifications

CAS Number

[1800004-01-6]

UNSPSC

12352005

Target

SARS-CoV

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

ClC1=CC2=C(C(NC3=CC=C(C(C4=CC=CC=C4)=C3)CN5CCCC5)=CC=N2)C=C1

Molecular Formula

C26H24ClN3

Molecular Weight

413.94

References & Citations

[1]Dávila B, et al. Unveiling novel pharmacophores and hit compounds for the development of anti-virals to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) . Bioorg Chem. 2025 Jul 4;163:108724.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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