AChE-IN-91
AChE-IN-91 (Compound 8u) is a AChE inhibitor with an IC50 of 0.05 μM. AChE-IN-91 has significant anticholinesterase activity, promising for neurological diseases like Alzheimer's disease (AD) research[1].
Product Specifications
CAS Number
1171708-92-1
UNSPSC
12352005
Target
Cholinesterase (ChE)
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
ClC1=CC=C(C=C1)C2NC(NC(C)=C2C3=NC(C4=CC=C(C=C4)F)=NO3)=O
Molecular Formula
C19H14ClFN4O2
Molecular Weight
384.79
References & Citations
[1]Ambatwar R, et al. Synthesis and evaluation of novel dihydropyrimidine-oxadiazole hybrid scaffolds as anticholinesterase agents: SAR and in-silico studies. Bioorg Med Chem Lett. 2025 Jul 4;128:130327.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE
Frequently Asked Questions
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