AChE-IN-91

AChE-IN-91 (Compound 8u) is a AChE inhibitor with an IC50 of 0.05 μM. AChE-IN-91 has significant anticholinesterase activity, promising for neurological diseases like Alzheimer's disease (AD) research[1].

Product Specifications

CAS Number

[1171708-92-1]

UNSPSC

12352005

Target

Cholinesterase (ChE)

Related Pathways

Neuronal Signaling

Field of Research

Neurological Disease

Smiles

ClC1=CC=C(C=C1)C2NC(NC(C)=C2C3=NC(C4=CC=C(C=C4)F)=NO3)=O

Molecular Formula

C19H14ClFN4O2

Molecular Weight

384.79

References & Citations

[1]Ambatwar R, et al. Synthesis and evaluation of novel dihydropyrimidine-oxadiazole hybrid scaffolds as anticholinesterase agents: SAR and in-silico studies. Bioorg Med Chem Lett. 2025 Jul 4;128:130327.