JY-5
JY-5 is an E3 ligase ligand. JY-5 can be used for synthesis of PROTAC JY-21 (HY-174975) [1].
Product Specifications
UNSPSC
12352005
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
CC(C)[Si](C(C)C)(C(C)C)C#C/N=N/C(C([N+]([O-])=O)=C1)=CC=C1OCC#C
Molecular Formula
C20H27N3O3Si
Molecular Weight
385.53
References & Citations
[1]Du J, et al. Azoacetylene Electrophiles for Proteome-wide Ligand and Target Discovery: Supporting Targeted Protein Degradation. J Med Chem. 2025 Jul 10;68 (13) :13516-13531.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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