FHND5071 (1H)
FHND5071 (1H) is a selective inhibitor targeting the RET (rearrangement during transfection) tyrosine kinase. FHND5071 (1H) is promising for research of RET-driven cancers (such as thyroid cancer, lung cancer, etc.) [1].
Product Specifications
CAS Number
[2493156-15-1]
UNSPSC
12352005
Target
RET
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
COC1=CC=C(C=N1)CN2C3CC2CN(C3)C4=NC=C(C=C4)C5=CC(N6CCN(CC6)C)=CN7N=CC(C#N)=C57
Molecular Formula
C30H33N9O
Molecular Weight
535.64
References & Citations
[1]Wang X, et al. Design and Discovery of Novel Selective RET Inhibitors with High Central Nervous System Penetration, Enhanced Pharmacokinetics, and Pharmacodynamics. J Med Chem. 2025 Jul 10;68 (13) :13990-14007.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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