CPD-2828
CPD-2828 is an orally active and selective IRE1α inhibitor with an IC50 value of 1.2 μM. CPD-2828 is promising for research of endoplasmic reticulum stress-related diseases (e.g., cancer, neurodegenerative diseases) [1].
Product Specifications
UNSPSC
12352005
Target
IRE1
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer; Neurological Disease
Smiles
O=CC1=C(O)C=CC2=C1OC(C(CC(N3CCC(C4=CC=C(NC(CC5)C(NC5=O)=O)C=C4)CC3)=O)=C2C)=O
Molecular Formula
C29H29N3O7
Molecular Weight
531.56
References & Citations
[1]Zerfas BL, et al. Structure-guided design of a truncated heterobivalent chemical probe degrader of IRE1α. RSC Med Chem. 2025 Mar 18.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IRE1α
Frequently Asked Questions
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