MGluR1 activator-1
MGluR1 activator-1 is a stable Vitamin K (HY-B2172) analogue and a mGluR1 activator that can penetrate the blood-brain barrier. mGluR1 activator-1 exhibits strong transcriptional activation via steroid and xenobiotic receptor as well as retinoic acid receptor. mGluR1 activator-1 induces neuronal differentiation in mouse neural progenitor cells. mGluR1 activator-1 can be used for the study of neurodegenerative disease such as Alzheimer’s[1].
Product Specifications
UNSPSC
12352005
Target
MGluR; Steroid Sulfatase
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
O=C(/C(C)=C/C=C/C(C)=C/CC/C(C)=C/CC1=C(C(C2=C(C1=O)C=CC=C2)=O)C)OC
Molecular Formula
C27H30O4
Molecular Weight
418.52
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR1
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