P2Y12R ligand-1
P2Y12R ligand-1 (Compound 41) is a high-affinity P2Y12R ligand with a Ki value of 17.1 nM. P2Y12R ligand-1 labeled with [18F] can be used in studies of brain PET imaging[1].
Product Specifications
UNSPSC
12352005
Target
P2Y Receptor
Related Pathways
GPCR/G Protein
Field of Research
Neurological Disease
Smiles
CCCC(C1=C(N(N=C1)C2=CC=C(C=C2)NC(C3=CN(C4=CC=C(C=C34)Cl)CC(N5CCC(CC5)CCF)=O)=O)C)=O
Molecular Formula
C32H35ClFN5O3
Molecular Weight
592.10
References & Citations
[1]Pincemail E, et al. Synthesis, Labeling, and Biological Evaluation of P2Y12 Receptor Radioligands for Positron Emission Tomography Imaging of Neuroinflammation. ACS Chem Neurosci. 2025 Jul 16;16 (14) :2639-2656.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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