CYP51-IN-26
CYP51-IN-26 is a CYP51 inhibitor with an IC50 value of approximately 0.40 μM. CYP51-IN-26 eradicates C. auris biofilms. CYP51-IN-26 demonstrates significantly improved intracellular uptake in an accumulation assay. CYP51-IN-26 protects against C. auris infection in both G. mellonella and D. melanogaster models. CYP51-IN-26 can be used for research on fungal infections[1].
Product Specifications
UNSPSC
12352005
Target
Cytochrome P450; Fungal
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
OC(C1=CC=C(C=C1F)F)(CN2CCC(CC2)NC3=NC=C(C=N3)F)CN4N=CN=C4
Molecular Formula
C20H22F3N7O
Molecular Weight
433.43
References & Citations
[1]Chen Y, et al. New Generation Modified Azole Antifungals against Multidrug-Resistant Candida auris. J Med Chem. 2025 Jul 10;68 (13) :14054-14071.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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