CRBN ligand-8-O-C6-NH2
CRBN ligand-8-O-C6-NH2 is an E3 ligase ligand-linker conjugate that incorporates a CRBN ligand and a linker. CRBN ligand-8-O-C6-NH2 can be used for synthesis of PROTAC ERα Degrader-11 (HY-174870).
Product Specifications
CAS Number
2407829-84-7
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Others
Smiles
O=C1C(CCC(N1)=O)N2C(C3=CC(OCCCCCCN)=CC4=CC=CC(C2=O)=C43)=O
Molecular Formula
C23H25N3O5
Molecular Weight
423.46
References & Citations
[1]Wu Y, et al. Discovery of ERα-targeting PROTACs with intrinsic fluorescence for precision theranostics of breast cancer. RSC Med Chem. 2025 May 22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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