CRBN ligand-8-O-C6-NH2

CRBN ligand-8-O-C6-NH2 is an E3 ligase ligand-linker conjugate that incorporates a CRBN ligand (HY-150831) and a linker. CRBN ligand-8-O-C6-NH2 can be used for synthesis of PROTAC ERα Degrader-11 (HY-174870) [1].

Product Specifications

CAS Number

[2407829-84-7]

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Others

Smiles

O=C1C(CCC(N1)=O)N2C(C3=CC(OCCCCCCN)=CC4=CC=CC(C2=O)=C43)=O

Molecular Formula

C23H25N3O5

Molecular Weight

423.46

References & Citations

[1]Wu Y, et al. Discovery of ERα-targeting PROTACs with intrinsic fluorescence for precision theranostics of breast cancer. RSC Med Chem. 2025 May 22.