IP300w
IP300w (Compound 9) is a Histone acetyltransferase p300 (KAT3B) inhibitor. iP300w can be used for synthesis of PROTAC BT-O2C.
Product Specifications
CAS Number
3055107-60-0
UNSPSC
12352005
Target
Histone Acetyltransferase; Ligands for Target Protein for PROTAC
Related Pathways
Epigenetics; PROTAC
Field of Research
Cancer
Smiles
O=C(O)CN1N=CC(C2=CC3=C([C@](C(N4CC(N(CC5=CC=C(F)C=C5)[C@@H](C)C(F)(F)F)=O)=O)(C[C@H]3F)NC4=O)C=C2)=C1
Molecular Formula
C28H24F5N5O5
Molecular Weight
605.51
References & Citations
[1]Marsh GP, et al. Development of p300-targeting degraders with enhanced selectivity and onset of degradation. RSC Med Chem. 2025 Mar 3;16 (5) :2049-2060.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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