Pomalidomide-C2-PEG-NHCO-C2-COOH
Pomalidomide-C2-PEG-NHCO-C2-COOH is a conjugate of the CRBN ligand and the linker (E3 Ligase Ligand-Linker Conjugate). Pomalidomide-C2-PEG-NHCO-C2-COOH can be used for synthesizing PROTAC ASK1 degrader dASK1 (HY-174862).
Product Specifications
CAS Number
2376050-06-3
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
O=C(NCCOCCNC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)CCC(O)=O
Molecular Formula
C21H24N4O8
Molecular Weight
460.44
References & Citations
[1]Sarkar HS, et al. Rational design and discovery of potent PROTAC degraders of ASK1: a targeted therapy in MASH. RSC Med Chem. 2025 Jun 6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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