(S, R, S) -AHPC-CO-C2-PEG-NHCO-C2-COOH
(S, R, S) -AHPC-CO-C2-PEG-NHCO-C2-COOH is a synthetic E3 ubiquitin ligase ligand-linker conjugate that can be used to synthesize PROTACs such as dASK1-VHL (HY-174858) [1].
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
CC(C)(C)[C@@H](C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C=C2)C3=C(N=CS3)C)=O)=O)NC(CCOCCNC(CCC(O)=O)=O)=O
Molecular Formula
C31H43N5O8S
Molecular Weight
645.77
References & Citations
[1]Himadri Sekhar Sarkar, et al. Rational design and discovery of potent PROTAC degraders of ASK1: a targeted therapy in MASH. RSC Med Chem. 2025 Jun 6. doi: 10.1039/d5md00252d.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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