ASK1 ligand 1
ASK1 ligand 1 is a binding ligand for ASK1 and can be used to synthesize PROTACs such as dASK1-VHL (HY-174858) [1].
Product Specifications
CAS Number
[3064087-54-0]
UNSPSC
12352005
Target
ASK1; Ligands for Target Protein for PROTAC
Related Pathways
Apoptosis; PROTAC
Field of Research
Cancer
Smiles
O=C(NC1=NC(C2=NN=CN2C(C)C)=CC=C1)C3=CC(N)=C(F)C=C3F
Molecular Formula
C17H16F2N6O
Molecular Weight
358.35
References & Citations
[1]Himadri Sekhar Sarkar, et al. Rational design and discovery of potent PROTAC degraders of ASK1: a targeted therapy in MASH. RSC Med Chem. 2025 Jun 6. doi: 10.1039/d5md00252d.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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