HBeAg ligand 1
HBeAg ligand 1 (Compound S2) is a HBeAg inhibitor. HBeAg ligand 1 can be used for synthesis of PROTAC HBeAg degrader-1 (HY-174856) [1].
Product Specifications
CAS Number
[2361022-13-9]
UNSPSC
12352005
Target
HBV; Ligands for Target Protein for PROTAC
Related Pathways
Anti-infection; PROTAC
Field of Research
Infection
Smiles
O=C(C1=C(CN2CCN(C(OC(C)(C)C)=O)CC2)NC(C3=NC=CS3)=N[C@H]1C4=CC=C(F)C=C4Cl)OC
Molecular Formula
C25H29ClFN5O4S
Molecular Weight
550.05
References & Citations
[1]Hales LT, et al. VHL-independent degradation of hepatitis B virus e antigen (HBeAg) by VHL-binding chimeric small molecules. RSC Med Chem. 2025 Mar 28.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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