PROTAC HBeAg degrader-1
PROTAC HBeAg degrader-1 is a PROTAC targeting degradation agent for HBeAg. PROTAC HBeAg degrader-1 recruits the VHL E3 ligase but degrades HBV protein HBeAg through VHL-independent mechanism. PROTAC HBeAg degrader-1 decreases levels of secreted and intracellular HBeAg. PROTAC HBeAg degrader-1 can be used for the research of hepatitis B virus (HBV). (Structure Note: Pink: HBeAg ligand ; Blue: VHL Ligand (HY-125845) ; Black: linker; E3-linker (HY-135045) )
Product Specifications
UNSPSC
12352005
Target
HBV; PROTACs
Related Pathways
Anti-infection; PROTAC
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
O=C(C1=C(CN2CCN(C(CCCCC(N[C@@H](C(C)(C)C)C(N3[C@H](C(NCC4=CC=C(C5=C(C)N=CS5)C=C4)=O)C[C@@H](O)C3)=O)=O)=O)CC2)NC(C6=NC=CS6)=N[C@H]1C7=CC=C(F)C=C7Cl)OC
Molecular Formula
C48H57ClFN9O7S2
Molecular Weight
990.60
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Von Hippel-Lindau (VHL)
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Human IgG Immunoglobulin (IG266), CF405S conjugate, 0.1mg/mL
Mucin 1 / EMA / Episialin / CD227 (VU-2G7), CF640R conjugate, 0.1mg/mL
ACTH (Adrenocorticotrophic Hormone) (AH26), CF640R conjugate, 0.1mg/mL
