TdT-IN-1

TdT-IN-1 (Compound 8c) is a selective and non-nucleoside terminal deoxynucleotidyl transferase (TdT) inhibitor with IC50 s of 0.11 and 0.19 μM for Mg2+ and Mn2+. TdT-IN-1 can be used for leukaemias and skin cancer research[1].

Product Specifications

UNSPSC

12352005

Target

DNA/RNA Synthesis

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Smiles

O=C(O)/C(O)=C/C(/C=C/C1=CNC=C1C2=CC=CC=C2)=O

Molecular Formula

C16H13NO4

Molecular Weight

283.28

References & Citations

[1]Madia VN, et al. Exploring structure-activity relationships of pyrrolyl diketo acid derivatives as non-nucleoside inhibitors of terminal deoxynucleotidyl transferase enzyme. J Enzyme Inhib Med Chem. 2025 Dec;40 (1) :2496782.