VCP/p97 IN-2
VCP/p97 IN-2 (Compound V13) is a VCP/p97 inhibitor with IC50 of 32 nM for p97. VCP/p97 IN-2 has excellent antitumor activities and significantly inhibits tumor growth in Molm-13 xenograft mice model. VCP/p97 IN-2 can be used for acute myeloid leukemia (AML) research[1].
Product Specifications
CAS Number
[3007658-94-5]
UNSPSC
12352005
Target
P97
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
CC1=CC2=C(C=CC=C2C(O)=O)N1C3=NC4=C(C(NCC5=CC=CC=C5)=N3)CCCN4
Molecular Formula
C24H23N5O2
Molecular Weight
413.47
References & Citations
[1]Wang X, et al. Design and Synthesis of Novel 5,6,7,8-Tetrahydropyrido[2,3-D]pyrimidine Derivatives as VCP/p97 Inhibitors for the Treatment of Acute Myeloid Leukemia (AML) . Drug Des Devel Ther. 2025 May 27;19:4457-4479.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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