P97-IN-1
P97-IN-1 is an orally active p97 inhibitor (IC50 = 26 nM) . p97-IN-1 can significantly inhibit the proliferation of tumor cells. p97-IN-1 can be used for research on acute myeloid leukemia (AML) [1].
Product Specifications
CAS Number
3007658-96-7
UNSPSC
12352005
Target
P97
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
CONC(C1=CC=CC2=C1C=C(N2C3=NC4=C(C(NCC5=CC=CC=C5)=N3)CCCN4)C)=O
Molecular Formula
C25H26N6O2
Molecular Weight
442.51
References & Citations
[1]Wang X, et al. Design and Synthesis of Novel 5,6,7,8-Tetrahydropyrido[2,3-D]pyrimidine Derivatives as VCP/p97 Inhibitors for the Treatment of Acute Myeloid Leukemia (AML) . Drug Des Devel Ther. 2025 May 27;19:4457-4479.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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