EGFR/HER2-IN-19
EGFR/HER2-IN-19 (Compound L1) is a dual inhibitor against epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2) . EGFR/HER2-IN-19 is promising for research of cancers driven by EGFR/HER2[1].
Product Specifications
CAS Number
2229835-58-7
UNSPSC
12352005
Target
EGFR
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
COC(C=C1N=CN=C(C1=C2)NC3=CC(Cl)=C(C=C3)OCC4=CC(F)=CC=C4)=C2OCCCN5CCNCCNCCNCC5
Molecular Formula
C33H41ClFN7O3
Molecular Weight
638.18
References & Citations
[1]El Mehdi K, et al. Discovery of Novel Dual EGFR/HER2 Inhibitors Using Integrated Docking, Molecular Dynamics, and MMGBSA Computational Approaches[J]. ChemistrySelect, 2025, 10 (21) : e01410.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ErbB2/HER2
Frequently Asked Questions
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